INT32482

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Context Info
Confidence 0.18
First Reported 1987
Last Reported 1997
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.26
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ghrh, Prl) extracellular space (Ghrh)
Anatomy Link Frequency
median eminence 1
Ghrh (Rattus norvegicus)
Prl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sumatriptan 11 99.46 Very High Very High Very High
Clonidine 2 97.84 Very High Very High Very High
Enkephalin 2 93.84 High High
Endogenous opioid 1 91.68 High High
Opioid 3 84.16 Quite High
agonist 2 76.80 Quite High
Central nervous system 1 69.28 Quite High
Disease Link Frequency Relevance Heat
Obesity 1 98.08 Very High Very High Very High
Alcohol Addiction 1 84.36 Quite High
Acromegaly 1 75.00 Quite High
Eating Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover we have evaluated in intact male rats the effect of exogenous GH on median eminence (ME) GHRH stores and the ability of FK 33-824 to stimulate GH and prolactin (PRL) secretion and of exogenous GHRH to induce GH secretion.
GHRH Positive_regulation (stimulate) of prolactin in median eminence
1) Confidence 0.18 Published 1987 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2957419 Disease Relevance 0 Pain Relevance 0.53
GHRH did not increase PRL.
GHRH Neg (not) Positive_regulation (increase) of PRL
2) Confidence 0.08 Published 1993 Journal Psychoneuroendocrinology Section Abstract Doc Link 8265735 Disease Relevance 0.18 Pain Relevance 0.21
In acromegalics, SU did not change the slight GHRH-induced increase in PRL levels.
GHRH Positive_regulation (increase) of PRL associated with sumatriptan
3) Confidence 0.02 Published 1997 Journal Recenti Prog Med Section Abstract Doc Link 9233053 Disease Relevance 0.07 Pain Relevance 0.87

General Comments

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