INT324827

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Hmgb1, Bad) mitochondrion (Bad) cell morphogenesis (Hmgb1)
DNA binding (Hmgb1) lipid binding (Bad) cell proliferation (Bad)
Anatomy Link Frequency
neutrophils 1
Hmgb1 (Mus musculus)
Bad (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 1 99.62 Very High Very High Very High
cytokine 14 96.64 Very High Very High Very High
Inflammatory mediators 1 75.36 Quite High
metalloproteinase 1 73.36 Quite High
chemokine 1 68.80 Quite High
Inflammation 67 66.40 Quite High
Inflammatory response 5 46.16 Quite Low
agonist 2 42.12 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 2 100.00 Very High Very High Very High
INFLAMMATION 69 74.96 Quite High
Adhesions 1 69.20 Quite High
Injury 15 48.64 Quite Low
Disease 36 5.00 Very Low Very Low Very Low
Sepsis 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 7 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, expression of monoamine oxidase B and the anti-apoptosis protein Bcl-xl was increased in neutrophils by HMGB1 but not by LPS.
HMGB1 Neg (not) Positive_regulation (increased) of anti-apoptosis protein Bcl-xl in neutrophils associated with apoptosis and monoamine
1) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.43 Pain Relevance 0.36

General Comments

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