INT324828

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ELANE, Ecm1) signal transduction (Ecm1) extracellular space (Ecm1)
peptidase activity (ELANE) proteinaceous extracellular matrix (Ecm1) enzyme binding (Ecm1)
ELANE (Homo sapiens)
Ecm1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 2 71.28 Quite High
Nicotine 1 60.68 Quite High
Inflammation 67 50.48 Quite High
cytokine 14 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 10 91.52 High High
Necrosis 3 75.68 Quite High
Cv Unclassified Under Development 1 71.28 Quite High
Reperfusion Injury 2 70.56 Quite High
Hepatotoxicity 2 68.08 Quite High
Injury 15 54.00 Quite High
INFLAMMATION 69 50.48 Quite High
Endotoxemia 1 43.44 Quite Low
Targeted Disruption 2 39.92 Quite Low
Disease 36 16.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of this process has been demonstrated; for example, release of immune-stimulatory HS fragments from the ECM in vivo can be mediated by the proteolytic action of elastase [182].
elastase Positive_regulation (mediated) of Localization (release) of ECM
1) Confidence 0.00 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.61 Pain Relevance 0.09

General Comments

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