INT324836

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Nox4, ROS1) cell differentiation (ROS1) cell proliferation (ROS1)
mitochondrion (Nox4) oxidoreductase activity (Nox4) cell morphogenesis (Nox4)
Nox4 (Mus musculus)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 5 62.84 Quite High
Inflammation 67 50.00 Quite Low
cytokine 14 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 1 71.36 Quite High
INFLAMMATION 69 62.48 Quite High
Disease 36 5.00 Very Low Very Low Very Low
Injury 15 5.00 Very Low Very Low Very Low
Sepsis 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 7 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Autoimmune Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAD(P)H oxidase 4 (Nox4) modulates the production of LPS-induced reactive oxygen species (ROS) by interacting with the cytoplasmic TIR domain of TLR4 [68, 69].
Nox4 Regulation (modulates) of Gene_expression (production) of ROS
1) Confidence 0.01 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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