INT324884

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ece1) peptidase activity (Ece1) Golgi apparatus (Ece1)
plasma membrane (Ece1)
Ece1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 9 96.96 Very High Very High Very High
metalloproteinase 62 74.88 Quite High
Dismenorea 1 71.12 Quite High
Inflammation 9 38.00 Quite Low
Hippocampus 1 13.96 Low Low
bradykinin 1 12.64 Low Low
Central nervous system 1 12.40 Low Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-term Labor 13 99.08 Very High Very High Very High
Infection 35 97.80 Very High Very High Very High
Targeted Disruption 16 96.28 Very High Very High Very High
Premature Birth 40 84.12 Quite High
Dysmenorrhea 1 71.12 Quite High
Disease 42 63.12 Quite High
Alzheimer's Dementia 9 50.00 Quite Low
Pre-eclampsia 1 47.96 Quite Low
Cancer 4 40.76 Quite Low
Hypertension 4 40.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequently, we have shown that ECE-1 is upregulated in our mouse model of PTL and that PTD is controlled with the ETA receptor antagonist BQ-123 and with silencing of ECE-1 mRNA [68] (Figure 2).
Positive_regulation (upregulated) of ECE-1 associated with antagonist and pre-term labor
1) Confidence 0.37 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913859 Disease Relevance 0.61 Pain Relevance 0.18
Interestingly, both ECE-1 and ECE-2 mRNA levels were enhanced when cell cultures were treated with A???
Positive_regulation (enhanced) of ECE-1
2) Confidence 0.15 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989646 Disease Relevance 0.25 Pain Relevance 0.04

General Comments

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