INT324887

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp8) extracellular space (Mmp8) extracellular region (Mmp8)
proteinaceous extracellular matrix (Mmp8)
Anatomy Link Frequency
amniotic fluid 4
Mmp8 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 44 93.48 High High
cytokine 12 55.28 Quite High
Inflammation 16 54.88 Quite High
antagonist 18 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premature Birth 80 99.40 Very High Very High Very High
Infection 70 98.52 Very High Very High Very High
Rupture 12 96.92 Very High Very High Very High
Pre-term Labor 26 69.48 Quite High
INFLAMMATION 22 54.88 Quite High
Reprotox - General 1 2 46.08 Quite Low
Hypertension 6 5.00 Very Low Very Low Very Low
Birth Weight 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An increase in midtrimester concentrations of amniotic fluid MMP-8, IL-6, and angiogenin are risk factors for early spontaneous preterm delivery (<32 weeks).
Positive_regulation (increase) of Localization (concentrations) of MMP-8 in amniotic fluid associated with premature birth
1) Confidence 0.10 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913859 Disease Relevance 0.58 Pain Relevance 0.16
MMP-8 is released during neutrophil activation, and amniotic fluid concentrations are elevated both in patients with intraamniotic infection and in patients with negative amniotic fluid cultures who deliver preterm.
Positive_regulation (elevated) of Localization (released) of MMP-8 in amniotic fluid associated with infection
2) Confidence 0.09 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913859 Disease Relevance 0.62 Pain Relevance 0.10

General Comments

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