INT324890

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.09
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Timp2) nucleus (Timp2)
Anatomy Link Frequency
amniotic cavity 2
Timp2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 30 100.00 Very High Very High Very High
palliative 43 96.28 Very High Very High Very High
cytokine 6 64.04 Quite High
Inflammation 8 63.64 Quite High
antagonist 9 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rupture 6 97.24 Very High Very High Very High
Cancer 38 93.36 High High
Pre-term Labor 13 78.24 Quite High
Premature Birth 40 77.76 Quite High
Hepatocellular Cancer 58 72.04 Quite High
Infection 35 64.80 Quite High
INFLAMMATION 11 63.64 Quite High
Lifespan 8 52.88 Quite High
Metastasis 24 43.88 Quite Low
Reprotox - General 1 1 13.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TIMP2 was down-regulated with reductions in TIMP2 levels to 15.6% of control levels (P < 0.05, Figure 2B).
Negative_regulation (down) of Negative_regulation (regulated) of TIMP2
1) Confidence 0.40 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2976755 Disease Relevance 0.53 Pain Relevance 0.47
Moreover, Maymon et al. (2001) found a decrease in tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in association with term and preterm parturition, term and preterm rupture of fetal membranes, and microbial invasion of the amniotic cavity [50].
Negative_regulation (decrease) of Negative_regulation (inhibitor) of TIMP-2 in amniotic cavity associated with rupture and metalloproteinase
2) Confidence 0.16 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2913859 Disease Relevance 0.56 Pain Relevance 0.21

General Comments

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