INT324908

Context Info Confidence 0.47 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.33 Pain Relevance 0

mitochondrion (TP53, BAX) nucleus (TP53, BAX) endoplasmic reticulum (TP53, BAX) cytoplasm (TP53, BAX) cytosol (TP53, BAX) cell differentiation (TP53)

TP53 (Homo sapiens) BAX (Homo sapiens)

Pain Link Frequency Relevance Heat abdominal pain 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 33 99.92 Lung Cancer 1 82.16 Death 9 76.68 Cancer 58 74.64 Malignant Neoplastic Disease 9 50.00 Recurrence 2 9.20 Metastasis 13 5.00 Disease 8 5.00 Endometrial Cancer 5 5.00 Reprotox - General 1 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

P53 is known to regulate Bax expression, with inactivation of p53 leading to reduced Bax protein levels [69,70].

P53 Regulation (regulate) of Gene_expression (expression) of Bax

1) Confidence 0.47 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2913917 Disease Relevance 1.33 Pain Relevance 0

General Comments

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