INT324955

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.96
Pain Relevance 2.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgam) nucleus (Itgam)
Anatomy Link Frequency
microglia 2
Itgam (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 39 99.90 Very High Very High Very High
Morphine 39 98.00 Very High Very High Very High
Duloxetine 33 95.36 Very High Very High Very High
Analgesic 18 94.56 High High
Serotonin 9 91.76 High High
Hyperalgesia 126 90.88 High High
allodynia 45 89.84 High High
Pain management 3 80.64 Quite High
medulla 6 78.76 Quite High
Snapping jaw 57 77.12 Quite High
Disease Link Frequency Relevance Heat
Nociception 30 97.52 Very High Very High Very High
Injury 75 91.04 High High
Hyperalgesia 126 90.88 High High
Neuropathic Pain 48 89.84 High High
Pain 108 80.64 Quite High
Temporomandibular Joint Syndrome 57 77.12 Quite High
Hypersensitivity 30 76.48 Quite High
INFLAMMATION 72 63.60 Quite High
Facial Pain 15 55.40 Quite High
Tendon Injuries 33 42.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For fluorescence staining (phosphorylation at serine 896 of the NR1 subunit, P-NR1; GFAP, glial fibrillary acidic protein; CD11b, cluster of differentiation 11b; NeuN), the sections were incubated with Streptavidin-Alexa Fluor 568 or 488 (1:600, Molecular Probes, Eugene, OR) for 1 h.
Phosphorylation (phosphorylation) of CD11b
1) Confidence 0.37 Published 2010 Journal Mol Pain Section Body Doc Link PMC2914030 Disease Relevance 0.10 Pain Relevance 0.22
In the same region, persistent upregulation of NMDA receptor NR1 phosphorylation and protein expression and increased expression of glial markers glial fibrillary acidic protein (astroglia) and CD11b (microglia) were found.
Phosphorylation (phosphorylation) of CD11b in microglia associated with nmda receptor
2) Confidence 0.28 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2914030 Disease Relevance 0.95 Pain Relevance 0.87
NMDA receptor expression and phosphorylation were upregulated, as well as GFAP and CD11b, markers of astroglia and microglia, respectively.
Phosphorylation (phosphorylation) of CD11b in microglia associated with nmda receptor
3) Confidence 0.12 Published 2010 Journal Mol Pain Section Body Doc Link PMC2914030 Disease Relevance 0.90 Pain Relevance 1.32

General Comments

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