INT325058

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.40
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Igf1) extracellular region (Igf1)
Anatomy Link Frequency
dentate gyrus 1
Igf1 (Rattus norvegicus)
Ang (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurotransmitter 3 89.60 High High
Inflammation 19 62.60 Quite High
Central nervous system 36 46.60 Quite Low
Hippocampus 5 35.60 Quite Low
Intracerebroventricular 1 24.00 Low Low
chemokine 25 5.00 Very Low Very Low Very Low
Glutamate 18 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 28 100.00 Very High Very High Very High
Diabetes Mellitus 3 90.08 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 83 75.80 Quite High
Toxicity 4 68.72 Quite High
Infection 34 63.80 Quite High
Insulin Resistance 3 63.44 Quite High
INFLAMMATION 26 62.60 Quite High
Disease 12 17.48 Low Low
Retinoblastoma 1 13.56 Low Low
Stress 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hippocampal neural progenitor cells express the insulin receptor (IR) and IGF-1 receptors, and insulin and IGF-1 are known to stimulate ANG in the dentate gyrus.
IGF-1 Positive_regulation (stimulate) of ANG in dentate gyrus associated with neurodegenerative disease
1) Confidence 0.04 Published 2010 Journal J Neuroimmune Pharmacol Section Body Doc Link PMC2914283 Disease Relevance 1.40 Pain Relevance 0.08

General Comments

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