INT325072

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 0.88
Pain Relevance 0.24

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extracellular space (Xcl1) extracellular region (Xcl1) cell-cell signaling (Xcl1)
Anatomy Link Frequency
dorsal 1
brain structures 1
ventral 1
Xcl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 24 73.24 Quite High
agonist 8 61.16 Quite High
Enkephalin 8 55.92 Quite High
Cannabinoid receptor 8 42.32 Quite Low
Endocannabinoid 16 38.52 Quite Low
Opioid 8 32.36 Quite Low
Neuropeptide 8 29.28 Quite Low
monoamine 8 12.84 Low Low
drug abuse 16 5.00 Very Low Very Low Very Low
narcan 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 120 92.04 High High
Hyperphagia 16 88.64 High High
Weight Gain 64 87.36 High High
Attention Deficit Hyperactivity Disorder 40 20.68 Low Low
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Drug Dependence 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, early- and mid-pubertal animals were tested in Progressive Ratio responding for SCM and c-fos protein expression in reward-associated brain structures was examined after odor conditioning for SCM.
Gene_expression (expression) of SCM in brain structures
1) Confidence 0.33 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Abstract Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0.04
Limited-free SCM intake
Gene_expression (intake) of SCM
2) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0.09 Pain Relevance 0
In the present study c-fos protein levels were measured in dorsal and ventral striatum after presentation of a SCM-associated odor cue in rats of pubertal (pd 40 and 50) and adult age (pd 90).
Gene_expression (presentation) of SCM in ventral
3) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0.09
We found a transient increase in SCM consumption and motivational incentive for SCM during puberty.
Gene_expression (consumption) of SCM
4) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Abstract Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0.03
Repeated measurement of SCM consumption in adult rats revealed no re-test effect (repeated measurement ANOVA, F1.7, 18.9 =?
Gene_expression (consumption) of SCM
5) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0.45 Pain Relevance 0
Higher consumption of SCM during the short experimental access of 15?
Gene_expression (consumption) of SCM
6) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0.34 Pain Relevance 0
These data demonstrate that repeated testing for SCM intake does not produce habituation nor sensitization for this food reward and therefore indicates that the characteristic course of SCM intake during adolescence is not related to any confounding factors.


Gene_expression (intake) of SCM
7) Confidence 0.25 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0
In the present study c-fos protein levels were measured in dorsal and ventral striatum after presentation of a SCM-associated odor cue in rats of pubertal (pd 40 and 50) and adult age (pd 90).
Gene_expression (presentation) of SCM in dorsal
8) Confidence 0.09 Published 2010 Journal Frontiers in Behavioral Neuroscience Section Body Doc Link PMC2914567 Disease Relevance 0 Pain Relevance 0.09

General Comments

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