INT325156

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CDKN1B, CDK2) nucleoplasm (CDKN1B, CDK2) cytoplasm (CDKN1B, CDK2)
cytosol (CDKN1B, CDK2) nucleus (CDKN1B, CDK2) cell cycle (CDKN1B, CDK2)
CDKN1B (Homo sapiens)
CDK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 22 53.76 Quite High
Cancer 26 51.52 Quite High
Colon Cancer 25 50.00 Quite Low
Death 5 34.08 Quite Low
Malaria 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Hepatitis 2 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we speculated that the resulting increased p21Cip1 and p27Kip1, by binding to and consequently inhibiting the cyclin E/CDK2 complex activity, potentiated the cell cycle arrest in G0/G1 phase, as also reported by others [28].
p27Kip1 Negative_regulation (inhibiting) of CDK2
1) Confidence 0.49 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2914703 Disease Relevance 0.11 Pain Relevance 0

General Comments

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