INT325236

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Sstr2) plasma membrane (Sstr2) cytoplasm (Sstr2)
signal transducer activity (Sstr2)
Sstr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 18 84.52 Quite High
Inflammation 29 68.88 Quite High
dexamethasone 2 54.68 Quite High
agonist 9 52.16 Quite High
cytokine 17 29.16 Quite Low
Dopamine 2 13.76 Low Low
antagonist 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pituitary Cancer 8 93.28 High High
Anaphylaxis 22 91.64 High High
Nelson Syndrome 3 91.40 High High
Acromegaly 4 88.00 High High
Adenoma 5 76.00 Quite High
Acth-secreting Pituitary Adenoma 7 71.32 Quite High
INFLAMMATION 35 68.88 Quite High
Pituitary Acth Hypersecretion 3 50.00 Quite Low
Rhinitis 1 9.32 Low Low
Cushing's Syndrome /

Hypercortisolism

30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, our data demonstrates that IgE-mediated activation is associated with reduction of ST2 expression and an increased release of sST2.
Positive_regulation (increased) of Localization (release) of sST2
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2914748 Disease Relevance 0.31 Pain Relevance 0.07
This observation could be explained with the lack of glucocorticoid-induced down-regulation of sst2, as mentioned above.52
Positive_regulation (induced) of Localization (regulation) of sst2
2) Confidence 0.18 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2963160 Disease Relevance 0.50 Pain Relevance 0.16

General Comments

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