INT325359

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.41 Pain Relevance 0

nucleus (Aes)

Aes (Rattus norvegicus)

Pain Link Frequency Relevance Heat corticosteroid 2 48.00 Pain 9 5.00 rheumatoid arthritis 2 5.00 Osteoarthritis 2 5.00 palliative 2 5.00 Spinal cord 1 5.00 alcohol 1 5.00 Bioavailability 1 5.00 Pain score 1 5.00 nud 1 5.00

Disease Link Frequency Relevance Heat Death 6 84.16 Disease 17 74.60 Osteoporosis 56 73.80 Infection 1 68.04 Toxicity 1 56.72 Aseptic Necrosis Of Bone 2 43.00 Malignant Neoplastic Disease 6 42.04 Metastasis 5 41.76 Arrhythmias 2 Under Development 8 34.28 Postmenopausal Osteoporosis 11 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the HORIZON-PFT study, the number of patients with AEs was significantly higher in the ZOL group (95.5% ZOL vs 93.9% placebo; P = 0.002), driven primarily by larger number of AEs associated with postdose symptoms.28 However, in the HORIZON-RFT study, the difference in the number of AEs between both groups was not significant (82.3% ZOL vs 80.6% placebo).43

Negative_regulation (number) of Positive_regulation (number) of AEs

1) Confidence 0.02 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2915556 Disease Relevance 0.41 Pain Relevance 0

General Comments

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