INT325380

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl) extracellular region (Ghrl) cytoplasm (Ghrl)
Ghrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antidepressant 12 98.98 Very High Very High Very High
Eae 6 96.92 Very High Very High Very High
sSRI 11 89.84 High High
nud 4 72.44 Quite High
fluoxetine 1 71.92 Quite High
Action potential 2 68.00 Quite High
Raphe 1 27.20 Quite Low
Hippocampus 6 26.12 Quite Low
Ventral tegmentum 9 20.96 Low Low
Nucleus accumbens 2 9.92 Low Low
Disease Link Frequency Relevance Heat
Appetite Loss 20 99.92 Very High Very High Very High
Gastrointestinal Disease 3 94.68 High High
Advanced Or Metastatic Breast Cancer 1 91.36 High High
Adverse Drug Reaction 4 89.12 High High
Vomiting 7 87.84 High High
Injury 1 82.20 Quite High
Anxiety Disorder 23 76.28 Quite High
Dyspepsia 4 72.44 Quite High
Sprains And Strains 6 70.16 Quite High
Stress 29 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has recently been shown that rikkunshito ameliorates cisplatin-induced anorexia by mediating an increase in the circulating ghrelin concentration.
Positive_regulation (mediating) of Positive_regulation (increase) of ghrelin associated with appetite loss
1) Confidence 0.45 Published 2010 Journal International Journal of Peptides Section Abstract Doc Link PMC2915625 Disease Relevance 1.09 Pain Relevance 0.08
We have shown that ghrelin's ability to decrease immobility in the forced swim test is dependent on the presence of orexin [9], and previous work has demonstrated that the antidepressant-like responses to calorie restriction (which also causes an increase in ghrelin) requires orexin [29].
Positive_regulation (causes) of Positive_regulation (increase) of ghrelin associated with antidepressant and eae
2) Confidence 0.32 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2915752 Disease Relevance 0.27 Pain Relevance 0.27

General Comments

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