INT325411

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 1
Tm2d1 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 2 80.32 Quite High
Spinal cord 3 62.92 Quite High
Eae 12 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Pyramidal cell 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 12 100.00 Very High Very High Very High
Targeted Disruption 46 97.46 Very High Very High Very High
Disease 88 94.56 High High
Death 9 92.72 High High
Amyloid Plaque 15 87.84 High High
Frontotemporal Dementia 2 43.80 Quite Low
Tauopathy 6 42.08 Quite Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Toxicity 10 5.00 Very Low Very Low Very Low
Cognitive Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A triple transgenic mouse model expressing the mutant transgenes PS1 (M146V), APPSW, and P301L tau was generated by the group of LaFerla to examine the interactions between beta-amyloid, neuronal dysfunction and neurofibrillary tangles [63].
beta-amyloid Binding (interactions) of in neuronal associated with targeted disruption and alzheimer's dementia
1) Confidence 0.01 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915753 Disease Relevance 0.71 Pain Relevance 0.07

General Comments

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