INT325433

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.41
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Csf2) extracellular region (Csf2) plasma membrane (Mapt)
cytoskeleton (Mapt) nucleus (Mapt) enzyme binding (Mapt)
Anatomy Link Frequency
neuronal 1
Csf2 (Mus musculus)
Mapt (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 48 5.00 Very Low Very Low Very Low
positron emission tomography 27 5.00 Very Low Very Low Very Low
Inflammation 21 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
monoamine 6 5.00 Very Low Very Low Very Low
long-term potentiation 3 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 477 99.84 Very High Very High Very High
Dementia 48 94.68 High High
Aging 9 93.92 High High
Frontotemporal Dementia 21 82.92 Quite High
Vascular Dementia 9 81.56 Quite High
Alzheimer's Dementia 30 22.72 Low Low
Cognitive Disorder 42 8.56 Low Low
Amyloid Plaque 48 5.00 Very Low Very Low Very Low
INFLAMMATION 27 5.00 Very Low Very Low Very Low
Disease Progression 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ELISA study using all antibodies has showed increased CSF concentration of p-tau in AD patients.
CSF Binding (concentration) of p-tau associated with disease
1) Confidence 0.12 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915796 Disease Relevance 1.48 Pain Relevance 0
The experimental evidences of high CSF concentrations of p-tau in only AD patients have suggested that p-tau is not a simple marker of axonal damage and neuronal degeneration, as t-tau, but it is more closely related to AD pathology and the formation of NFT.

5.3.

CSF Binding (concentrations) of p-tau in neuronal associated with disease
2) Confidence 0.10 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915796 Disease Relevance 1.45 Pain Relevance 0
ELISA study using all antibodies has showed increased CSF concentration of p-tau in AD patients.
CSF Binding (concentration) of p-tau associated with disease
3) Confidence 0.09 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915796 Disease Relevance 1.48 Pain Relevance 0

General Comments

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