INT325464

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SRGN) extracellular region (SRGN) Golgi apparatus (SRGN)
Anatomy Link Frequency
stroma 1
SRGN (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 1 99.80 Very High Very High Very High
metalloproteinase 11 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Endocannabinoid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 11 99.80 Very High Very High Very High
Uveitis 15 97.68 Very High Very High Very High
Glaucoma 34 95.80 Very High Very High Very High
Hirsutism 1 95.24 Very High Very High Very High
Malignant Neoplastic Disease 1 86.64 High High
Pigment Disorder 2 71.84 Quite High
Ocular Toxicity (including Many Sub-types) 8 61.60 Quite High
Trichiasis 1 60.96 Quite High
Alopecia 2 59.04 Quite High
Ocular Hypertension 156 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro increase in PGE2 by latanoprost also suggests its role as an intracellular signaling agent to promote gene transcription and melanogenesis.22 Potential problems with excess melanin include melanin granule release and inflammatory response in the stroma, melanin-induced anterior uveitis, or secondary pigment-induced glaucoma.228

Hypertrichosis

Localization (release) of melanin granule in stroma associated with hirsutism, inflammatory response, glaucoma and uveitis
1) Confidence 0.01 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2915861 Disease Relevance 0.73 Pain Relevance 0.05

General Comments

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