INT325838

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Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Dnm1, Dnm2) GTPase activity (Dnm1, Dnm2) protein complex (Dnm1, Dnm2)
cytoplasm (Dnm1, Dnm2) plasma membrane (Dnm2) nucleus (Dnm2)
Anatomy Link Frequency
brain 1
Dnm1 (Mus musculus)
Dnm2 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 7 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Pyramidal cell 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Somatosensory cortex 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 34 50.32 Quite High
Epilepsy 15 50.00 Quite Low
Hearing Impairment 4 48.16 Quite Low
Ataxia 7 47.60 Quite Low
Generalized Epilepsy 3 36.92 Quite Low
Congenital Anomalies 4 33.36 Quite Low
Neurological Disease 4 23.32 Low Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This remains a possibility as we find that DNM1aFtfl can interact with DNM2 to some extent, both in COS-7 cells and also in brain (unpublished data), however we find no evidence of colocalization by immunofluorescence (unpublished data).
DNM1aFtfl Binding (interact) of DNM2 in brain
1) Confidence 0.50 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2916854 Disease Relevance 0.05 Pain Relevance 0

General Comments

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