INT325850
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
For the coagulase-fibrinogen interaction, coagulase was injected at 100 pM, 500 pM, 1 nM, 5 nM, 10 nM, 25 nM, 50 nM, 100 nM, and 300 nM for 60 seconds of association followed by 60 seconds of dissociation and the chip was regenerated as described above. | |||||||||||||||
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vWbp antibodies interfere with the association between coagulases and clotting factors. | |||||||||||||||
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The KD for the coagulase·prothrombin interaction is lower than the reported affinity for the D1D2 domain alone [36]; we currently do not appreciate the basis for this difference. | |||||||||||||||
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Using this assay, we observed that staphylococcal variants lacking coagulase activity displayed delays in clotting time, ? | |||||||||||||||
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Clinical isolates of the human pathogen Staphylococcus aureus secrete coagulase (Coa), a polypeptide that binds to and activates prothrombin, thereby converting fibrinogen to fibrin and promoting clotting of plasma or blood. | |||||||||||||||
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General Comments
This test has worked.