INT325854

Context Info Confidence 0.67 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 3 Disease Relevance 1.98 Pain Relevance 0

pigmentation (Hps3) cytoplasm (Hps3)

Hps3 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 6 5.00 Pain 3 5.00 Arthritis 3 5.00

Disease Link Frequency Relevance Heat Abscess 189 94.72 Sprains And Strains 75 91.68 Death 12 89.80 Staphylococcus Infection 45 89.44 Bacteremia 30 88.56 Infection 45 83.52 Coagulation Disorder 54 82.84 Rhinitis 15 64.12 Disease 39 50.00 Yersinia Infection 3 10.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

When probed for expression of coagulases with specific antibodies, we observed Coa secretion by wild-type S. aureus as well as the ?

Positive_regulation (When) of Gene_expression (expression) of coa

1) Confidence 0.67 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2916881 Disease Relevance 0.62 Pain Relevance 0

Introduction of pvWbp-coa, a plasmid providing for the expression of both coagulase genes, into ?

Positive_regulation (providing) of Gene_expression (expression) of coa

2) Confidence 0.49 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2916881 Disease Relevance 0.60 Pain Relevance 0

In contrast, deletion of both coagulase genes caused a dramatic defect; ?

Positive_regulation (caused) of Gene_expression (deletion) of coa

3) Confidence 0.49 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2916881 Disease Relevance 0.77 Pain Relevance 0

General Comments

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