INT325862

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Wbp5) biological_process (Wbp5)
Anatomy Link Frequency
blood 1
Wbp5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 27.04 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 26 97.24 Very High Very High Very High
Bacteremia 20 95.84 Very High Very High Very High
Abscess 126 95.00 High High
Staphylococcus Infection 30 94.20 High High
Cv Unclassified Under Development 2 93.12 High High
Sprains And Strains 50 89.28 High High
Mrsa Infection 12 72.76 Quite High
Immunization 18 66.48 Quite High
Body Weight 6 65.36 Quite High
Infection 30 52.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Generating isogenic variants of S. aureus Newman, a virulent clinical isolate [18], we report here that mutants with defects in both coagulase genes, coa and vWbp, display virulence defects in three mouse models for staphylococcal disease: survival in blood, lethal bacteremia and renal abscess formation.
Negative_regulation (defects) of vWbp in blood associated with bacteremia, abscess and disease
1) Confidence 0.02 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2916881 Disease Relevance 1.22 Pain Relevance 0
Interestingly, vWbp┬Ěprothrombin activity (Fig. 5F) was impeded by both specific vWbp antibodies (P?
Negative_regulation (impeded) of vWbp
2) Confidence 0.02 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2916881 Disease Relevance 0.21 Pain Relevance 0

General Comments

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