INT325936

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Context Info
Confidence 0.69
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Ezr) cytosol (Ezr) nucleolus (Ezr)
plasma membrane (Ezr) cytoskeleton (Ezr) intracellular (Ezr)
Anatomy Link Frequency
plasma 2
Ezr (Mus musculus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 22 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 54 98.88 Very High Very High Very High
Adhesions 6 92.60 High High
Stress 2 88.40 High High
Apoptosis 2 79.00 Quite High
Melanoma 4 76.16 Quite High
Malignant Neoplastic Disease 10 55.60 Quite High
Metastasis 82 50.00 Quite Low
Pancreatic Cancer 44 50.00 Quite Low
Anaplastic Astrocytoma 2 40.88 Quite Low
Rhabdomyosarcoma 4 32.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been recently reported that phosphorylation of ezrin is required for metastatic behavior of tumor cells [31].
Positive_regulation (required) of Phosphorylation (phosphorylation) of ezrin associated with cancer
1) Confidence 0.69 Published 2010 Journal J Transl Med Section Body Doc Link PMC2916894 Disease Relevance 0.28 Pain Relevance 0
Phosphorylation of ezrin induces its translocation from the cytoplasm to the plasma membranes of microvillus and confers the ability of binding to plasma membrane and actin filaments [9-12].
Positive_regulation (induces) of Phosphorylation (Phosphorylation) of ezrin in plasma
2) Confidence 0.50 Published 2010 Journal J Transl Med Section Body Doc Link PMC2916894 Disease Relevance 0.34 Pain Relevance 0

General Comments

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