INT326013

Context Info Confidence 0.08 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.85 Pain Relevance 0

cytoskeleton (UBR4) nucleus (UBR4) ligase activity (UBR4) cytoplasm (UBR4)

UBR4 (Homo sapiens) UBR4 - V600E (1)

Pain Link Frequency Relevance Heat Glutamate 1 26.48 Pain 1 5.00

Disease Link Frequency Relevance Heat Nevus 2 99.80 Melanoma 19 95.20 Cancer 9 81.24 Disease 1 60.08 Pain 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Likewise, in our cohort of 14 congenital nevi, we also detected four with BRAF mutations, all heterozygous V600E.

Gene_expression (detected) of V600E (V600E) associated with nevus

1) Confidence 0.08 Published 2010 Journal J Transl Med Section Body Doc Link PMC2917408 Disease Relevance 0.85 Pain Relevance 0

General Comments

This test has worked.