INT326044

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Mki67) nucleolus (Mki67) nucleus (Mki67)
intracellular (Mki67) molecular_function (Mki67) cellular_component (Mki67)
Mki67 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 66 99.56 Very High Very High Very High
cytokine 8 23.56 Low Low
sSRI 5 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
antidepressant 5 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 2 78.72 Quite High
Cirrhosis 1 32.56 Quite Low
Sepsis 1 19.72 Low Low
Neurodegenerative Disease 19 5.00 Very Low Very Low Very Low
Depression 5 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Exsanguination 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect is noted even before any "triggering" for regeneration took place, as rats pre-treated with rhEPO showed increased expression of both Ki 67 and PCNA before hepatectomy was performed.
Negative_regulation (showed) of Gene_expression (expression) of Ki 67
1) Confidence 0.12 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2917416 Disease Relevance 0.08 Pain Relevance 0
In the second part of this experiment, as expected from Experiment 1, icv K252a for 14 days reduced Ki67 positive cells expression in 14-day fluoxetine -treated rats compared to those receiving fluoxetine and icv saline (One-way ANOVA: F (3,15) ?
Negative_regulation (reduced) of Gene_expression (expression) of Ki67 associated with fluoxetine
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965105 Disease Relevance 0 Pain Relevance 0.83

General Comments

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