INT326057

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOA1, APOE) lipid metabolic process (APOA1, APOE) extracellular space (APOA1, APOE)
extracellular region (APOA1, APOE) plasma membrane (APOA1, APOE) aging (APOE)
Anatomy Link Frequency
adipocytes 2
APOA1 (Homo sapiens)
APOE (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 12 38.40 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 153 99.32 Very High Very High Very High
Cardiovascular Disease 12 97.92 Very High Very High Very High
Disorder Of Lipid Metabolism 63 95.28 Very High Very High Very High
Atherosclerosis 21 89.40 High High
Stress 3 53.92 Quite High
INFLAMMATION 12 38.40 Quite Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low
Overweight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The regulation of apoE secretion by apoA-I, is neither dependent upon an increase in gene transcription, nor upon increased release from the Golgi (figures 5 and 6).
apoA-I Regulation (regulation) of Localization (secretion) of apoE
1) Confidence 0.54 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2917427 Disease Relevance 0.23 Pain Relevance 0
Moreover, it is noteworthy that inhibition of adenylate cyclase or PKA does not modify the activator effect of apoA-I on apoE secretion (data not shown).
apoA-I Regulation (effect) of Localization (secretion) of apoE
2) Confidence 0.54 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2917427 Disease Relevance 0.34 Pain Relevance 0
Effect of apoA-I on cholesterol release and apoE secretion in human mature adipocytes

Background

apoA-I Regulation (Effect) of Localization (secretion) of apoE in adipocytes associated with obesity
3) Confidence 0.24 Published 2010 Journal Lipids Health Dis Section Title Doc Link PMC2917427 Disease Relevance 0.78 Pain Relevance 0

General Comments

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