INT326065

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOE, LCAT) lipid metabolic process (APOE, LCAT) extracellular space (APOE, LCAT)
extracellular region (APOE, LCAT) aging (APOE) Golgi apparatus (APOE)
APOE (Homo sapiens)
LCAT (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 21 98.12 Very High Very High Very High
Obesity 51 76.24 Quite High
Atherosclerosis 7 54.56 Quite High
Cardiovascular Disease 4 20.52 Low Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ApoE plays a key role in this process, contributing both to the efflux of cholesterol [5], and to the expansion in the size of HDLs, by increasing the activity of LCAT, which esterifies free cholesterol within the HDL particles [6].
ApoE Positive_regulation (increasing) of LCAT associated with disorder of lipid metabolism
1) Confidence 0.53 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2917427 Disease Relevance 0.84 Pain Relevance 0

General Comments

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