INT326066

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOA1, HMGCR) endoplasmic reticulum (HMGCR) peroxisome (HMGCR)
enzyme binding (APOA1) transmembrane transport (APOA1) lipid metabolic process (APOA1)
APOA1 (Homo sapiens)
HMGCR (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 51 79.08 Quite High
Disorder Of Lipid Metabolism 21 35.88 Quite Low
Atherosclerosis 7 5.00 Very Low Very Low Very Low
Cardiovascular Disease 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thirdly, apoA-I does not induce an increase in extracellular cholesterol by the activation of HMG-CoA reductase since the use of specific inhibiting molecules does not block the effect of the apoA-I (figure 4).
apoA-I Neg (not) Positive_regulation (induce) of Positive_regulation (activation) of HMG-CoA reductase
1) Confidence 0.17 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2917427 Disease Relevance 0.19 Pain Relevance 0

General Comments

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