INT326126

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.34
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (S100A1, TP53) cytoplasm (S100A1, TP53) nucleus (S100A1, TP53)
cell differentiation (TP53) nucleoplasm (TP53) mitochondrion (TP53)
Anatomy Link Frequency
lung 1
S100A1 (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 3 59.00 Quite High
Kinase C 1 44.08 Quite Low
chemokine 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 10 94.20 High High
Stomach Cancer 1 93.64 High High
Lung Cancer 2 92.92 High High
Pancreatic Cancer 1 92.40 High High
Brain Tumor 1 91.52 High High
Colon Cancer 62 88.64 High High
Metastasis 8 83.92 Quite High
Cancer 43 79.36 Quite High
Breast Cancer 4 59.68 Quite High
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The S100 family bind to p53 and regulate the oligomerization of p53.41 Copy number gain and high expression of the S100 family is reported in relation with progression and recurrence of stomach cancer,42 lung cancer, pancreatic cancer and brain tumor.42,43 This suggests that S100A2 is likely to be linked with CRC.
S100 Binding (bind) of p53 in lung associated with lung cancer, colon cancer, pancreatic cancer, brain tumor, stomach cancer and recurrence
1) Confidence 0.04 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.34 Pain Relevance 0.09

General Comments

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