INT326137

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctnnb1) enzyme binding (Ctnnb1) DNA binding (Ctnnb1)
protein complex (Ctnnb1) cytoplasm (Ctnnb1) cell proliferation (Ctnnb1)
Ctnnb1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 4 29.24 Quite Low
COX2 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 62 98.08 Very High Very High Very High
Adhesions 1 97.86 Very High Very High Very High
Apoptosis 4 86.40 High High
Cancer 43 75.92 Quite High
Repression 3 73.92 Quite High
Recurrence 10 5.00 Very Low Very Low Very Low
Metastasis 8 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Mouth Cancer 2 5.00 Very Low Very Low Very Low
Lung Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SNAI1 is located at 20q13.1-q13.2, and is said to play a role in the regulation of the cell adhesion protein E-cadherin (CDH1).21 SNAI1 is also plays a role in phosphorylation through Axin and GSK-3beta for degradation of beta-catenin in proteasomes in the Wnt-signaling pathway.22 DCC is located at 18q21.3, and it is one of the membrane proteins with netrin-1 (NTN1) as a ligand.
Protein_catabolism (degradation) of beta-catenin associated with colon cancer and adhesions
1) Confidence 0.02 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.08 Pain Relevance 0

General Comments

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