INT326140

Context Info Confidence 0.17 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.87 Pain Relevance 0.06

cytosol (SULT1B1) small molecule metabolic process (SULT1B1) cytoplasm (SULT1B1)

SULT1B1 (Homo sapiens)

Pain Link Frequency Relevance Heat chemokine 4 69.84 cINOD 2 29.60 COX2 3 5.00 Kinase C 1 5.00

Disease Link Frequency Relevance Heat Repression 3 92.72 Colon Cancer 62 90.40 Lung Cancer 2 67.12 Hypoxia 1 66.20 Cancer 43 62.12 Breast Cancer 4 54.88 Recurrence 10 49.52 Metastasis 8 42.40 INFLAMMATION 1 29.04 Apoptosis 4 7.36

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Key:

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Anatomy

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High expression of SULT1B1 mRNA has been reported in normal colorectal samples, and it is thought to be related to carcinogenesis.30 Expression of SULT1B1 is a characteristic for normal colorectal tissue, so repression of SULT1B1 along with repression of UGT2B28 in CRC is thought to be related to tissue dedifferentiation.

Transcription (expression) of SULT1B1 associated with colon cancer and repression

1) Confidence 0.17 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 0.87 Pain Relevance 0.06

General Comments

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