INT326169

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (SLC6A1) plasma membrane (SLC6A1) transmembrane transport (SLC6A1)
SLC6A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
gABA 86 99.98 Very High Very High Very High
Analgesic 3 97.64 Very High Very High Very High
Bioavailability 1 97.36 Very High Very High Very High
agonist 8 96.84 Very High Very High Very High
central pain 20 93.44 High High
Central nervous system 17 90.64 High High
GABA receptor 2 85.60 High High
depression 2 55.48 Quite High
Serotonin 1 53.88 Quite High
monoamine 1 53.32 Quite High
Disease Link Frequency Relevance Heat
Scotoma 1 98.40 Very High Very High Very High
Pain 29 92.80 High High
Disease 4 83.84 Quite High
Toxicity 2 80.88 Quite High
Xerostomia 1 58.80 Quite High
Heart Rate Under Development 1 58.20 Quite High
Pressure Volume 2 Under Development 2 57.68 Quite High
Depression 2 55.48 Quite High
Constipation 1 50.24 Quite High
Granuloma 1 20.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, vigabatrin, a GABA agonist with good bioavailability and analgesic action, produced visual field defects in 1/3 of patients during therapy and tiagabine, a selective inhibitor of GABA transport (GAT1), took twenty years to bring to market.17,18
Localization (transport) of GAT1 associated with scotoma, gaba, analgesic, agonist and bioavailability
1) Confidence 0.13 Published 2010 Journal Perspect Medicin Chem Section Body Doc Link PMC2918363 Disease Relevance 0.72 Pain Relevance 1.24

General Comments

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