INT326378

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Rhoa, Ezr) cytoplasm (Rhoa, Ezr) cytosol (Rhoa, Ezr)
plasma membrane (Rhoa, Ezr) cytoskeleton (Rhoa, Ezr) cell differentiation (Rhoa)
Anatomy Link Frequency
brain 1
Rhoa (Mus musculus)
Ezr (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 62.72 Quite High
cerebral cortex 6 52.48 Quite High
Hippocampus 11 24.96 Low Low
interneuron 1 22.84 Low Low
Thalamus 5 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 16 85.20 High High
Fasciculation 13 20.80 Low Low
Neuritis 1 5.00 Very Low Very Low Very Low
Hypothermia 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Anuria 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we found that brain PC interacts with the Ezrin/NHERF1-2/RhoA-G complex, thereby suggesting that activation of this protein complex is responsible for the reduction in neurite growth and branching observed in PC loss-of-function models.
RhoA Binding (interacts) of Ezrin in brain
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0.17 Pain Relevance 0.06

General Comments

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