INT326383

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Rhoa, Gopc) plasma membrane (Rhoa, Gopc) cell differentiation (Rhoa)
transport (Gopc) mitochondrion (Rhoa) cell morphogenesis (Rhoa)
Anatomy Link Frequency
neural 1
Rhoa (Mus musculus)
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 6 36.00 Quite Low
Thalamus 5 29.28 Quite Low
Hippocampus 11 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mevalonate Kinase Deficiency 58 100.00 Very High Very High Very High
Adhesions 16 50.00 Quite Low
Fasciculation 13 5.00 Very Low Very Low Very Low
Fever 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Hypergammaglobulinemia 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-immunoprecipation analyses in brain lysates revealed that neural PC also interacts with RhoA and with the related small GTPase RhoG (Fig. 2h,i).
RhoA Binding (interacts) of Fig in neural
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
Incubation with simvastatin decreased the levels of membrane-bound RhoA in both control and MKD cells (Fig. 1b).
RhoA Binding (bound) of Fig associated with mevalonate kinase deficiency
2) Confidence 0.03 Published 2010 Journal J Inherit Metab Dis Section Body Doc Link PMC2946549 Disease Relevance 0.89 Pain Relevance 0

General Comments

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