INT326388

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 10
Disease Relevance 1.26
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PROC, Slc9a3r2) peptidase activity (PROC) extracellular space (PROC)
extracellular region (PROC) nucleus (Slc9a3r2) cytoplasm (Slc9a3r2)
Anatomy Link Frequency
kidney 4
podocytes 2
MDCK 2
Brain 1
Neural 1
PROC (Homo sapiens)
Slc9a3r2 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 60 59.36 Quite High
cytokine 20 49.44 Quite Low
interneuron 10 29.72 Quite Low
Hippocampus 110 25.84 Quite Low
Pyramidal cell 10 9.04 Low Low
Thalamus 50 5.00 Very Low Very Low Very Low
midbrain 10 5.00 Very Low Very Low Very Low
Peripheral nervous system 10 5.00 Very Low Very Low Very Low
Neuritis 10 5.00 Very Low Very Low Very Low
halothane 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 160 90.76 High High
Fasciculation 130 87.92 High High
Cancer 10 87.88 High High
Anuria 10 82.84 Quite High
Neuritis 10 5.00 Very Low Very Low Very Low
Hypothermia 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 10 5.00 Very Low Very Low Very Low
Stroke 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In kidney and MDCK cells, PC interacts with Ezrin and the sodium-hydrogen exchanger regulatory factor 1 and 2 (NHERF1/2) [25], [33], [34].
PC Binding (interacts) of sodium-hydrogen exchanger regulatory factor 1 and 2 in kidney
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
In kidney and MDCK cells, PC interacts with Ezrin and the sodium-hydrogen exchanger regulatory factor 1 and 2 (NHERF1/2) [25], [33], [34].
PC Binding (interacts) of NHERF1/2 in kidney
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
Two cytosolic adaptor proteins, Na+/H+-Exchanger Regulatory Factor 2 (NHERF2) and Ezrin, interact with PC in kidney [25].
PC Binding (interact) of NHERF2 in kidney
3) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0.34 Pain Relevance 0
Neural PC interacts with the ERM protein family, and with NHERF1/2 and RhoA/G.
PC Binding (interacts) of NHERF1/2 in Neural
4) Confidence 0.00 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2919383 Disease Relevance 0.25 Pain Relevance 0
Brain PC forms a protein complex with Ezrin, NHERF1/2 and RhoA/G
PC Binding (complex) of NHERF1/2 in Brain
5) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
In kidney podocytes PC forms a complex with Ezrin and the NHERF2, which promotes RhoA activation and stabilizes the actin cytoskeleton [25], [34].
PC Binding (forms) of NHERF2 in podocytes
6) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0.16 Pain Relevance 0.03
In kidney podocytes PC forms a complex with Ezrin and the NHERF2, which promotes RhoA activation and stabilizes the actin cytoskeleton [25], [34].
PC Binding (complex) of NHERF2 in podocytes
7) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0.16 Pain Relevance 0.03
Two cytosolic adaptor proteins, Na+/H+-Exchanger Regulatory Factor 2 (NHERF2) and Ezrin, interact with PC in kidney [25].
PC Binding (interact) of Exchanger Regulatory Factor 2 in kidney
8) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0.35 Pain Relevance 0
In kidney and MDCK cells, PC interacts with Ezrin and the sodium-hydrogen exchanger regulatory factor 1 and 2 (NHERF1/2) [25], [33], [34].
PC Binding (interacts) of sodium-hydrogen exchanger regulatory factor 1 and 2 in MDCK
9) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
In kidney and MDCK cells, PC interacts with Ezrin and the sodium-hydrogen exchanger regulatory factor 1 and 2 (NHERF1/2) [25], [33], [34].
PC Binding (interacts) of NHERF1/2 in MDCK
10) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0

General Comments

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