INT326447

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.32
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Mrgprb4) molecular_function (Mrgprb4) cellular_component (Mrgprb4)
biological_process (Mrgprb4) signal transducer activity (Mrgprb4)
Anatomy Link Frequency
neurons 2
Mrgprb4 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 4 92.40 High High
Spinal cord 8 90.12 High High
superficial lamina 4 89.08 High High
Neuropeptide 4 78.56 Quite High
nociceptor 316 76.96 Quite High
IPN 76 63.20 Quite High
Inflammation 56 52.40 Quite High
Neuropathic pain 140 51.04 Quite High
TRP channel 4 45.28 Quite Low
Kinase C 4 42.16 Quite Low
Disease Link Frequency Relevance Heat
Pruritus 4 89.64 High High
Cancer 4 63.76 Quite High
Inflammatory Pain 76 63.20 Quite High
INFLAMMATION 56 52.40 Quite High
Neuropathic Pain 176 51.04 Quite High
Targeted Disruption 56 26.88 Quite Low
Pain 80 13.76 Low Low
Hyperalgesia 28 5.00 Very Low Very Low Very Low
Nervous System Injury 24 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, expression of several Mrgpr class GPCRs (Mrgpra3, Mrgprb4, and Mrgprc11), which was eliminated in E-CKO mice [14,24], was fully "restored" in L-CKO mice (Fig. 1C).
Gene_expression (expression) of Mrgprb4
1) Confidence 0.65 Published 2010 Journal Mol Pain Section Body Doc Link PMC2919460 Disease Relevance 0 Pain Relevance 0.36
Tissue preparation, the in situ hybridization (ISH) procedure, and the probes for TRPM8, TRPV1, Mrgprc11, CGRP, Mrgprd, TRPC3, P2X3, Mrgpra3, Mrgprb4, TrkA, SCG10, DRASIC, Ret, and GluR5/Grik1, have been described previously [14,24,41].
Gene_expression (probes) of Mrgprb4
2) Confidence 0.56 Published 2010 Journal Mol Pain Section Body Doc Link PMC2919460 Disease Relevance 0.06 Pain Relevance 0
Another program B gene Mrgprc11 is expressed in both Mrgpra3+ and Mrgprb4+ neurons [24].
Gene_expression (expressed) of Mrgprb4 in neurons
3) Confidence 0.49 Published 2010 Journal Mol Pain Section Body Doc Link PMC2919460 Disease Relevance 0.26 Pain Relevance 0.20
Counting of Mrgprb4+ neurons in lumbar DRG showed no differences in control versus L-CKO mice (Fig. 1E).
Gene_expression (neurons) of Mrgprb4 in neurons
4) Confidence 0.49 Published 2010 Journal Mol Pain Section Body Doc Link PMC2919460 Disease Relevance 0 Pain Relevance 0.35

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox