INT326460

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1I2) signal transduction (NR1I2) oxidoreductase activity (Cyp4f18)
endoplasmic reticulum (Cyp4f18) nucleus (NR1I2)
NR1I2 (Homo sapiens)
Cyp4f18 (Mus musculus)
Pain Link Frequency Relevance Heat
carbamazepine 2 93.76 High High
antiepileptic Drug 6 92.84 High High
anesthesia 2 21.40 Low Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fracture Healing 2 79.36 Quite High
Convulsion 12 74.68 Quite High
Osteoporosis 9 74.32 Quite High
Injury 2 67.00 Quite High
Dislocations 1 64.56 Quite High
Hypocalcemia 1 64.16 Quite High
Hypercalcemia 1 62.72 Quite High
Compression Fractures 1 59.80 Quite High
Humeral Fractures 1 54.20 Quite High
Epilepsy 3 48.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pregnabe × receptor (PXR), a transcriptional regulator of CYP450, mediates the adverse effect on bone metabolism of both CYP450 inducers and inhibitors through stimulation of vitamin D catabolism and inhibition of 25-hydroxylation of vitamin D [16].
PXR Regulation (regulator) of CYP450
1) Confidence 0.01 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2919461 Disease Relevance 0.72 Pain Relevance 0.18

General Comments

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