INT32657

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Context Info
Confidence 0.08
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (Pomc) cytoplasm (Pomc) extracellular space (Pomc)
generation of precursor metabolites and energy (Pomc) signal transduction (Pomc) extracellular region (Pomc)
Pomc (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 12 100.00 Very High Very High Very High
Pain 4 75.00 Quite High
Antinociceptive 1 75.00 Quite High
monoamine 1 70.24 Quite High
agonist 1 68.56 Quite High
antinociception 2 67.28 Quite High
tail-flick 1 63.36 Quite High
intrathecal 1 59.08 Quite High
Disease Link Frequency Relevance Heat
Pain 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stimulation of these mu receptors by i.t. morphine or i.t. beta-endorphin together with the supraspinal effect of beta-endorphin resulted in an additive interaction.
Positive_regulation (resulted) of beta-endorphin Positive_regulation (Stimulation) of receptors associated with morphine
1) Confidence 0.08 Published 1988 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2974485 Disease Relevance 0.22 Pain Relevance 1.51

General Comments

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