INT326570

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90ab1) protein folding (Hsp90ab1) cytosol (Hsp90ab1)
mitochondrion (Hsp90ab1) intracellular (Hsp90ab1) response to stress (Hsp90ab1)
Hsp90ab1 (Mus musculus)
Csprs (Mus musculus)
Pain Link Frequency Relevance Heat
diabetic neuropathy 2 52.88 Quite High
hypoalgesia 4 50.00 Quite Low
Demyelination 10 5.00 Very Low Very Low Very Low
unmyelinated 7 5.00 Very Low Very Low Very Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
Painful diabetic neuropathy 1 5.00 Very Low Very Low Very Low
dorsal root ganglion 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 7 100.00 Very High Very High Very High
Stress 7 90.80 High High
Disease 2 88.72 High High
Diabetes Mellitus 40 77.64 Quite High
Disease Progression 1 76.08 Quite High
Apoptosis 3 65.04 Quite High
Neurodegenerative Disease 5 53.84 Quite High
Peripheral Neuropathy 2 52.88 Quite High
Hypoalagesia 4 50.00 Quite Low
Death 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hsp90 (heat-shock protein 90) is the master regulator of the HSR (heat-shock response) since it binds HSF1 (heat-shock factor 1).
Hsp90 Regulation (regulator) of HSR associated with shock
1) Confidence 0.08 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2919983 Disease Relevance 1.17 Pain Relevance 0.03

General Comments

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