INT326574

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Akt1, Hsp90ab1) cytosol (Akt1, Hsp90ab1) unfolded protein binding (Hsp90ab1)
mitochondrion (Hsp90ab1) transport (Akt1) aging (Akt1)
Akt1 (Mus musculus)
Hsp90ab1 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 10 86.76 High High
Potency 1 76.88 Quite High
hypoalgesia 4 50.00 Quite Low
unmyelinated 7 35.12 Quite Low
isoflurane 1 28.84 Quite Low
Sciatic nerve 3 19.00 Low Low
diabetic neuropathy 2 5.00 Very Low Very Low Very Low
Painful diabetic neuropathy 1 5.00 Very Low Very Low Very Low
dorsal root ganglion 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 10 86.76 High High
Death 14 86.04 High High
Diabetes Mellitus 40 50.00 Quite Low
Shock 7 50.00 Quite Low
Hypoalagesia 4 50.00 Quite Low
Stress 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Diabetes Complications 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although inhibiting Hsp90 can destabilize its association with client proteins such as Akt and lead to their degradation, 5 ?
Akt Binding (association) of Hsp90
1) Confidence 0.13 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2919983 Disease Relevance 0.17 Pain Relevance 0.08

General Comments

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