INT326575

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (JUN) nuclear chromosome (JUN) aging (JUN)
cell morphogenesis (Nrg1) DNA binding (JUN) cytoplasm (Nrg1)
Anatomy Link Frequency
Schwann cell 2
Nrg1 (Mus musculus)
JUN (Homo sapiens)
Pain Link Frequency Relevance Heat
Demyelination 10 99.64 Very High Very High Very High
Neuropathic pain 1 61.44 Quite High
Painful diabetic neuropathy 1 52.24 Quite High
hypoalgesia 4 50.00 Quite Low
unmyelinated 7 34.96 Quite Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
diabetic neuropathy 2 5.00 Very Low Very Low Very Low
dorsal root ganglion 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 10 99.64 Very High Very High Very High
Death 14 97.00 Very High Very High Very High
Apoptosis 3 87.28 High High
Neurodegenerative Disease 5 80.32 Quite High
Insulin Resistance 2 69.88 Quite High
Diabetes Mellitus 40 68.96 Quite High
Neuropathic Pain 3 61.44 Quite High
Diabetic Neuropathy 1 52.24 Quite High
Shock 7 50.00 Quite Low
Hypoalagesia 4 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, although increased expression of the c-jun transcription factor contributes to NRG1-induced demyelination, its phosphorylation by JNK is not essential to mediate Schwann cell degeneration (Parkinson et al., 2008).
NRG1 Positive_regulation (contributes) of Gene_expression (expression) of c-jun in Schwann cell associated with demyelination
1) Confidence 0.38 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2919983 Disease Relevance 0.86 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox