INT326603

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (DRD2) plasma membrane (DRD2) signal transducer activity (DRD2)
Anatomy Link Frequency
striatum 2
DRD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
dopamine receptor 2 99.96 Very High Very High Very High
positron emission tomography 46 97.60 Very High Very High Very High
Dopamine 78 95.84 Very High Very High Very High
monoamine 6 90.96 High High
Substantia nigra 6 81.36 Quite High
Neurotransmitter 2 73.76 Quite High
imagery 23 67.72 Quite High
midbrain 5 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 66 98.80 Very High Very High Very High
Nerve Degeneration 7 66.96 Quite High
Parkinsonian Disorders 39 64.88 Quite High
Movement Disorders 1 46.92 Quite Low
Parkinson's Disease 3 39.28 Quite Low
Tremor 12 25.60 Quite Low
Hypokinesia 5 24.32 Low Low
Congenital Anomalies 15 5.00 Very Low Very Low Very Low
Liver Disease 12 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Postsynaptic D2-dopamine receptors (D2Rs) either are not affected or are increased in the striatum of untreated PD patients (Antonini et al. 1994; Brooks et al. 1992; Rinne et al. 1990).
Neg (not) Regulation (affected) of Neg (not) Positive_regulation (increased) of D2R in striatum associated with dopamine receptor and disease
1) Confidence 0.44 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2920085 Disease Relevance 0.80 Pain Relevance 0.69

General Comments

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