INT326661

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.96
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Arc) extracellular region (Bdnf) plasma membrane (Arc)
cytoskeleton (Arc) cytoplasmic membrane-bounded vesicle (Bdnf) cytoskeleton organization (Arc)
Anatomy Link Frequency
neurons 2
Bdnf (Mus musculus)
Arc (Mus musculus)
Pain Link Frequency Relevance Heat
bDMF 36 100.00 Very High Very High Very High
intrathecal 20 99.92 Very High Very High Very High
Dorsal horn neuron 12 99.20 Very High Very High Very High
Spinal cord 50 90.48 High High
GABAergic 10 82.20 Quite High
allodynia 4 39.08 Quite Low
Thermal hyperalgesia 2 38.52 Quite Low
Neuropathic pain 8 36.48 Quite Low
Lasting pain 14 11.92 Low Low
Dorsal horn 24 9.68 Low Low
Disease Link Frequency Relevance Heat
Aids-related Complex 262 100.00 Very High Very High Very High
Nociception 82 50.00 Quite Low
Nervous System Injury 12 43.76 Quite Low
Neuropathic Pain 14 39.08 Quite Low
Hyperalgesia 6 38.52 Quite Low
Pain 56 11.92 Low Low
Targeted Disruption 68 5.04 Very Low Very Low Very Low
Depression 14 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Inflammatory Pain 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intrathecal injection of BDNF induces Arc/Arg3.1 mRNA expression
BDNF Positive_regulation (induces) of Gene_expression (expression) of Arc/Arg3.1 mRNA associated with aids-related complex, bdmf and intrathecal
1) Confidence 0.27 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 0.97 Pain Relevance 0.43
Intrathecal injection of brain-derived neurotrophic factor (BDNF) induced Arc/Arg3.1 mRNA expression in the superficial dorsal horn neurons (10 ± 1.7/section, n = 6).
brain-derived neurotrophic factor Positive_regulation (induced) of Gene_expression (expression) of Arc/Arg3.1 mRNA in neurons associated with aids-related complex, dorsal horn neuron, bdmf and intrathecal
2) Confidence 0.27 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 0.99 Pain Relevance 0.43

General Comments

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