INT326663

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.46
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Arc) extracellular region (Bdnf) plasma membrane (Arc)
cytoskeleton (Arc) cytoplasmic membrane-bounded vesicle (Bdnf) cytoskeleton organization (Arc)
Anatomy Link Frequency
dorsal horn 2
Bdnf (Mus musculus)
Arc (Mus musculus)
Pain Link Frequency Relevance Heat
bDMF 18 100.00 Very High Very High Very High
Glutamate 7 99.84 Very High Very High Very High
spinal dorsal horn 2 99.68 Very High Very High Very High
intrathecal 10 94.96 High High
qutenza 5 85.20 High High
IPN 4 82.88 Quite High
Dorsal horn neuron 6 79.16 Quite High
Neuropeptide 1 71.92 Quite High
Neurotransmitter 2 69.80 Quite High
Spinal cord 25 64.92 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 131 100.00 Very High Very High Very High
Nociception 41 100.00 Very High Very High Very High
Inflammatory Pain 4 82.88 Quite High
Pain 28 50.20 Quite High
INFLAMMATION 5 26.80 Quite Low
Targeted Disruption 34 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Neuropathic Pain 7 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, our findings are in line with the idea that release of glutamate and/or BDNF from activated nociceptive fibers are at least partly responsible for Arc/Arg3.1 induction in the spinal dorsal horn.
BDNF Regulation (responsible) of Positive_regulation (induction) of Arc/Arg3.1 in dorsal horn associated with nociception, glutamate, aids-related complex, spinal dorsal horn and bdmf
1) Confidence 0.16 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 1.46 Pain Relevance 0.88

General Comments

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