INT326762

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ARG2) small molecule metabolic process (ARG2) cellular nitrogen compound metabolic process (ARG2)
ARG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 90.32 High High
cytokine 14 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 108 76.32 Quite High
Cancer 74 61.28 Quite High
Malignant Neoplastic Disease 20 50.72 Quite High
Recurrence 2 16.72 Low Low
Hyperplasia 8 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The androgen induction of ARG2 was not blocked, even at the highest concentration of bicalutamide.
Negative_regulation (blocked) of Positive_regulation (induction) of ARG2
1) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0 Pain Relevance 0.05
Both the ARG1 and ARG2 induction following R1881 stimulation were inhibited by the siRNA treatment, which translated in the absence of an upregulation in arginase activity (Figure 2F).
Negative_regulation (inhibited) of Positive_regulation (induction) of ARG2
2) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0.25 Pain Relevance 0.04

General Comments

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