INT326781

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Context Info
Confidence 0.71
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.93
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ARG2) small molecule metabolic process (ARG2) cellular nitrogen compound metabolic process (ARG2)
ARG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 21.04 Low Low
cytokine 35 5.00 Very Low Very Low Very Low
palliative 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 270 99.84 Very High Very High Very High
Cancer 185 93.12 High High
Malignant Neoplastic Disease 50 74.96 Quite High
Recurrence 5 68.52 Quite High
Hyperplasia 20 55.40 Quite High
INFLAMMATION 5 21.04 Low Low
Toxicity 5 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Breast Cancer 5 5.00 Very Low Very Low Very Low
Colon Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in LNCaP cells, ARG2 mRNA expression was increased at 48 hours (p?
Transcription (expression) of ARG2
1) Confidence 0.71 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0.45 Pain Relevance 0
As for ARG2 expression, the LNCaP cell line expressed the highest levels of ARG2 mRNA (Figure 1A).
Transcription (levels) of ARG2
2) Confidence 0.71 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0.79 Pain Relevance 0
Low ARG2 mRNA expression was detected in the two HR cell lines DU145 and PC3 compared to the two HS PCa cell lines.
Transcription (expression) of ARG2 associated with reprotox - general 1
3) Confidence 0.71 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0.83 Pain Relevance 0
Based on the protein expression (Figure 1B, bottom panel) and on the arginase activity of PCa cells (Figure 1B, top panel), our data suggest that ARG2 may nonetheless have a more prominent role than ARG1 in the arginase activity potential of PCa cells [20].
Transcription (activity) of arginase associated with reprotox - general 1
4) Confidence 0.68 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 1.03 Pain Relevance 0
Low ARG2 mRNA expression was detected in the two HR cell lines DU145 and PC3 compared to the two HS PCa cell lines.
Transcription (detected) of ARG2 associated with reprotox - general 1
5) Confidence 0.53 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920336 Disease Relevance 0.84 Pain Relevance 0

General Comments

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