INT326805

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.57
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (KLK4) extracellular region (KLK4)
KLK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 4 84.08 Quite High
Piles 16 5.00 Very Low Very Low Very Low
headache 12 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
conotoxin 8 5.00 Very Low Very Low Very Low
Ziconotide 8 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Lasting pain 4 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 48 97.12 Very High Very High Very High
Sprains And Strains 12 88.16 High High
Shellfish Poisoning 44 79.68 Quite High
Poisoning 8 8.48 Low Low
Anorectal Disorders 16 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Death 8 5.00 Very Low Very Low Very Low
Tension-type Headache 8 5.00 Very Low Very Low Very Low
Frailty 4 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ability of bacteria to degrade PSTs has been further described by Smith et al., who screened marine bacterial isolates from various shellfish species for their ability to metabolize a range of PSTs, such as GTX1-5, STX and neoSTX, suggesting that bacteria might play an important role in the clearance of PSTs from bivalve molluscs [113].
Localization (range) of PSTs
1) Confidence 0.17 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.16 Pain Relevance 0
Metabolism of PSTs by humans has not been studied in depth.
Localization (Metabolism) of PSTs
2) Confidence 0.17 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.32 Pain Relevance 0.04
The PSTs can be broadly characterized as hydrophilic or hydrophobic, and can be divided into subgroups based on substituent side chains such as carbamate, sulfate, hydroxyl, hydroxybenzoate, or acetate.
Localization (divided) of PSTs
3) Confidence 0.17 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.09 Pain Relevance 0
Biotransformation of the PSTs by bacteria was first suggested many years ago by Kotaki et al., who proposed that marine bacteria, such as Vibrio and Pseudomonas spp., are capable of metabolizing PSTs [110].
Localization (Biotransformation) of PSTs
4) Confidence 0.17 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0 Pain Relevance 0

General Comments

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