INT326822

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (Cdk5) cytoplasm (Cdk5) cytosol (Cdk5)
nucleocytoplasmic transport (Cdk5) cell death (Cdk5) nucleolus (Cdk5)
Cdk5 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 24 98.64 Very High Very High Very High
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Intracerebroventricular 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Transient Ischemic Attack 1 99.40 Very High Very High Very High
Cv Unclassified Under Development 14 84.96 Quite High
Death 24 72.44 Quite High
Stroke 27 65.84 Quite High
Cv General 4 Under Development 5 8.76 Low Low
Myelodysplastic Syndromes 7 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Brain Hemorrhage 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that (R)-roscovitine reduced hyperphosporylation of the Tau protein, a major CDK5 target, after transient cerebral ischemia in rat, mainly by inhibiting CDK5 [21].
Negative_regulation (reduced) of Phosphorylation (hyperphosporylation) of CDK5 associated with transient ischemic attack and ischemia
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920814 Disease Relevance 0.43 Pain Relevance 0.12

General Comments

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