INT326925

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.47
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Unc79) cellular_component (Unc79) biological_process (Unc79)
Unc79 (Mus musculus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 18 99.92 Very High Very High Very High
substance P 12 99.18 Very High Very High Very High
anesthesia 6 79.60 Quite High
Dopamine 9 74.04 Quite High
isoflurane 21 64.44 Quite High
Central nervous system 6 54.76 Quite High
halothane 24 39.72 Quite Low
Eae 33 5.00 Very Low Very Low Very Low
alcohol 24 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 24 98.00 Very High Very High Very High
Targeted Disruption 12 90.68 High High
Sprains And Strains 78 5.00 Very Low Very Low Very Low
Body Weight 21 5.00 Very Low Very Low Very Low
Alcohol Addiction 12 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Decompression Sickness 9 5.00 Very Low Very Low Very Low
Helminth Infection 6 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 6 5.00 Very Low Very Low Very Low
Syncope 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ethanol may directly modulate the nca-encoded leak channel or perhaps indirectly modulate the channel through an effect on unc-79 and unc-80.
Regulation (modulate) of unc-79
1) Confidence 0.26 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.19 Pain Relevance 0.03
Ethanol may directly modulate the nca-encoded leak channel or perhaps indirectly modulate the channel through an effect on unc-79 and unc-80.
Regulation (effect) of unc-79
2) Confidence 0.26 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.19 Pain Relevance 0.03
Alternatively, ethanol might alter the release of neurotensin, substance P, or other neuromodulators in the VTA to influence NALCN/unc-79 function secondarily.
Regulation (influence) of unc-79 associated with ventral tegmentum and substance p
3) Confidence 0.23 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.09 Pain Relevance 0.50

General Comments

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