INT326931

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Context Info
Confidence 0.75
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.66
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Unc79) cellular_component (Unc79) biological_process (Unc79)
Anatomy Link Frequency
terminal portion 1
central nervous system 1
Unc79 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 99.36 Very High Very High Very High
Eae 33 93.28 High High
Dopamine 9 59.04 Quite High
Ventral tegmentum 18 52.72 Quite High
substance P 12 31.68 Quite Low
isoflurane 21 14.20 Low Low
halothane 24 5.00 Very Low Very Low Very Low
alcohol 24 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 78 86.72 High High
Body Weight 21 80.32 Quite High
Targeted Disruption 12 60.64 Quite High
Hypersensitivity 24 53.32 Quite High
Alcohol Addiction 12 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Decompression Sickness 9 5.00 Very Low Very Low Very Low
Helminth Infection 6 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 6 5.00 Very Low Very Low Very Low
Syncope 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because the unc-79 protein is widely expressed throughout the central nervous system, tissue-specific deletion using conditional mutagenesis or RNA interference may yield more specific results.
Gene_expression (expressed) of unc-79 protein in central nervous system associated with central nervous system
1) Confidence 0.75 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.05 Pain Relevance 0.13
To determine whether a full-length unc-79 protein was produced in mutants, we generated polyclonal antibodies against a C-terminal portion of the protein (see Figure 3C).
Gene_expression (produced) of unc-79 protein in terminal portion
2) Confidence 0.75 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.16 Pain Relevance 0.05
Taken together, these data strongly support the conclusion that the unc-79 mutation, and not some other lesion or polymorphism, is responsible for the observed phenotypes.


Gene_expression (mutation) of unc-79
3) Confidence 0.65 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2920847 Disease Relevance 0.44 Pain Relevance 0.05

General Comments

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